Fighting Kinase Drug Resistance with Caspase Activators
نویسندگان
چکیده
منابع مشابه
Laser Optofluidics in Fighting Multiple Drug Resistance
The book combines fields which experience increasing interest in recent years: optofluidics, microfluidics and fighting multiple drug resistance (MDR) seen as part of infectious diseases domain. Ther eported results are of interest for life sciences, environment quality control and biomedical basic and applied research. Biomedical specialists, chemists, physicists, public health experts and eve...
متن کاملFighting resistance.
A pioneer in the early identification of drug resistance in tuberculosis patients, Sir John Crofton and his colleagues' seminal research into multidrug therapy for tuberculosis patients in the 1950s laid the groundwork for the WHO-recommended tuberculosis treatment today. This is one of the last interviews he gave before he passed away on 3 November at the age of 97, after a career that spanned...
متن کاملKinase inhibitors and cytotoxic drug resistance.
The Src family consists of a group of nonreceptor tyrosine kinases and includes Src, Lyn, Hck, Yes, and Fyn (1). These kinases are critically involved in diverse cellular processes, including cell survival, proliferation, motililty, adhesion, and transformation, among others. Elevated or constitutive activation of Src as well as over-expression are commonly observed in epithelial tumors, most n...
متن کاملAMP-Dependent Protein Kinase Activators
A patent inability to properly use glycolytic and fatty acid substrates and progressive insulin resistance characterize non–insulin dependent diabetes mellitus. Curiously, the failing myocardium may also share these unfavorable characteristics. Insights from the clinical arena indicate a significant relationship between insulin resistance and New York Heart Association heart failure classificat...
متن کاملDrug Resistance
عفونت و تهاجم ارگانیسم های انگلی به بدن، عامل اصلی بیماری و مرگ انسانها از آغاز بشریت بوده است . در حقیقت بسیاری از اشکال حیات بدون غلبه بر ارگانیسم های زنده دیگر، قادر به ادامه زندگی نخواهند بود. انسانها معمولا مستعد تهاجم ارگانیسم های کوچکتری مانند کرمها، آمیب ها، قارچها، باکتریها و ویروسها هستند. این عوامل مکان خاصی را در بدن انتخاب کرده، مواد ضروری لازم برای حیات و تکثیر خود را دریافت نموده...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cell Chemical Biology
سال: 2018
ISSN: 2451-9456
DOI: 10.1016/j.chembiol.2018.08.001